Claude Code
Codex
Cursor
GitHub Copilot
Gemini CLIAbout this skill
Grade the human-genetic validation of a drug target on a causality-ranked evidence ladder (Mendelian/rare-variant > coding GWAS+colocalization > Mendelian randomization > non-coding GWAS), scoring direction-of-effect concordance, tractability, and on-target safety read-across. Produces a 0-13 composite tier from Open Targets, the Genetic Priority Score, gnomAD constraint, and a cis-MR/PheWAS scan. Activate when assessing whether a target hypothesis is genetically supported, before mechanism-risk or PoS modeling, when screening an early-discovery asset, or when learning what separates a PCSK9-class target from a hopeful GWAS hit.
Quick start
- Copy the install prompt. Use the green button above this README.
- Send it to your agent. Paste it into your coding agent’s chat and send.
- Review the setup. Your agent checks the skill’s instructions, requirements, and installation scope.
Review, license & listing details
This is an imported listing. We haven’t certified its safety, license, or compatibility. Skills may include executable scripts.
Only SKILL.md was scanned. Supporting files and scripts were not checked. No safety grade has been assigned.
0 potential findings · Scanned 11/4/2026 · Scanner 0.2.1
Content SHA-256: f38071521d71f60e1e76777abd80d15c2a74b9f9b444b01bc9c38d4c7864cf1f
About this listing
- Category
- Science & research
- Reported license
- MIT
- Listing language (estimated)
- English
- Review status
- Not individually reviewed
- Agent compatibility
- Atlas installation supports Claude Code, Codex, and Cursor. Skill-specific dependencies and features are checked during setup.