Claude Code
Codex
Cursor
GitHub Copilot
Gemini CLIAbout this skill
Deterministic developability/liability gate for GENERATED antibody Fv sequences (e.g. an AlphaFold-Multimer / RFdiffusion+ProteinMPNN designed binder, or an antibody language model) with karyon. Use AFTER designing an antibody/binder and BEFORE expressing or advancing it — answers "is this Fv developable, or does it carry a liability that makes it undruggable?" with a pass/fail verdict and legible per-reason explanations (an unpaired cysteine, an N-glycosylation sequon in a CDR, an extreme CDR-H3 length or isoelectric point — and, disclosed, the deamidation/isomerization/oxidation hotspots, fragmentation sites, and hydrophobicity/charge proxies even approved antibodies carry). Pure stdlib — no GPU, no network, no numpy. Input is the VH (+VL) amino-acid sequence; single-domain VHH/nanobodies are supported.
Quick start
- Copy the install prompt. Use the green button above this README.
- Send it to your agent. Paste it into your coding agent’s chat and send.
- Review the setup. Your agent checks the skill’s instructions, requirements, and installation scope.
Review, license & listing details
This is an imported listing. We haven’t certified its safety, license, or compatibility. Skills may include executable scripts.
Only SKILL.md was scanned. Supporting files and scripts were not checked. No safety grade has been assigned.
0 potential findings · Scanned 11/4/2026 · Scanner 0.2.1
Content SHA-256: cd91e405483ad9b56915022e93fa5e4bacfe0951a6d1e920b7dccdd4135d19e0
About this listing
- Category
- General
- Reported license
- Not specified
- Listing language (estimated)
- English
- Review status
- Not individually reviewed
- Agent compatibility
- Atlas installation supports Claude Code, Codex, and Cursor. Skill-specific dependencies and features are checked during setup.