Compares how a rhythm CHANGES between conditions, genotypes, treatments, tissues, or ages (differential rhythmicity), classifying each feature as gain-of-rhythm, loss-of-rhythm, phase change, amplitude change, unchanged-rhythmic, or arrhythmic-in-both, and distinguishing differential EXPRESSION (condition main effect) from differential RHYTHMICITY (condition x time interaction). Uses model-based approaches that borrow strength across conditions - LimoRhyde (sin/cos interaction terms in a limma/edgeR/DESeq2 design), dryR (BIC model selection across >=2 conditions), compareRhythms (direct gain/loss/change/same classification), DODR, CircaCompare - instead of the detect-then-Venn anti-pattern that overestimates reprogramming. Use when testing whether rhythms differ between conditions/genotypes/tissues/ages, classifying gain/loss/phase/amplitude change, or separating differential expression from differential rhythmicity. Not for detecting rhythms in one condition (see temporal-genomics/circadian-rhythms).
Install with
Claude CodeCodexCursorGitHub CopilotGemini CLI
Supported by the Atlas install prompt. Skill-specific requirements vary.
Skill stats
Skills1CategoryEngineeringStars0
About this skill
Compares how a rhythm CHANGES between conditions, genotypes, treatments, tissues, or ages (differential rhythmicity), classifying each feature as gain-of-rhythm, loss-of-rhythm, phase change, amplitude change, unchanged-rhythmic, or arrhythmic-in-both, and distinguishing differential EXPRESSION (condition main effect) from differential RHYTHMICITY (condition x time interaction). Uses model-based approaches that borrow strength across conditions - LimoRhyde (sin/cos interaction terms in a limma/edgeR/DESeq2 design), dryR (BIC model selection across >=2 conditions), compareRhythms (direct gain/loss/change/same classification), DODR, CircaCompare - instead of the detect-then-Venn anti-pattern that overestimates reprogramming. Use when testing whether rhythms differ between conditions/genotypes/tissues/ages, classifying gain/loss/phase/amplitude change, or separating differential expression from differential rhythmicity. Not for detecting rhythms in one condition (see temporal-genomics/circadian-rhythms).
Quick start
Copy the install prompt. Use the green button above this README.
Send it to your agent. Paste it into your coding agent’s chat and send.
Review the setup. Your agent checks the skill’s instructions, requirements, and installation scope.
Compares how a rhythm CHANGES between conditions, genotypes, treatments, tissues, or ages (differential rhythmicity), classifying each feature as gain-of-rhythm, loss-of-rhythm, phase change, amplitude change, unchanged-rhythmic, or arrhythmic-in-both, and distinguishing differential EXPRESSION (condition main effect) from differential RHYTHMICITY (condition x time interaction). Uses model-based approaches that borrow strength across conditions - LimoRhyde (sin/cos interaction terms in a limma/edgeR/DESeq2 design), dryR (BIC model selection across >=2 conditions), compareRhythms (direct gain/loss/change/same classification), DODR, CircaCompare - instead of the detect-then-Venn anti-pattern that overestimates reprogramming. Use when testing whether rhythms differ between conditions/genotypes/tissues/ages, classifying gain/loss/phase/amplitude change, or separating differential expression from differential rhythmicity. Not for detecting rhythms in one condition (see temporal-genomics/circadian-rhythms).
About this listing
Category
Engineering
Reported license
Not specified
Listing language (estimated)
English
Review status
Not individually reviewed
Agent compatibility
Atlas installation supports Claude Code, Codex, and Cursor. Skill-specific dependencies and features are checked during setup.
Claude Code
Codex
Cursor
GitHub Copilot
Gemini CLI